BrainyJoy system requirements state that you will need at least 2 GB of RAM. If possible, make sure your have 4 GB of RAM in order to run BrainyJoy to its full potential. An Intel Core 2 Duo E8400 CPU is required at a minimum to run BrainyJoy. The cheapest graphics card you can play it on is an NVIDIA GeForce 6100.
BrainyJoy will run on PC system with XP and upwards.