An Intel Core 2 Duo U7600 CPU is required at a minimum to run Destruction. Destruction system requirements state that you will need at least 2 GB of RAM. The cheapest graphics card you can play it on is an NVIDIA GeForce 7100 / nForce 630i. You will need at least 143 MB of free disk space to install Destruction.
Destruction will run on PC system with Windows 7 and upwards.