An Intel Core i3-530 CPU is required at a minimum to run Mosaic. However, the developers recommend a CPU greater or equal to an Intel Core i5-650 to play the game. The cheapest graphics card you can play it on is an NVIDIA GeForce 6100. In terms of game file size, you will need at least 3 GB of free disk space available. Mosaic system requirements state that you will need at least 1 GB of RAM. Additionally, the game developers recommend somewhere around 2 GB of RAM in your system.
Mosaic will run on PC system with TBA and upwards. Additionally it has Mac and Linux versions.