In terms of game file size, you will need at least 500 MB of free disk space available. An Intel Core 2 Duo E4600 CPU is required at a minimum to run Ant Queen. Whereas, an Intel Core i5-650 is recommended in order to run it. The minimum memory requirement for Ant Queen is 512 MB of RAM installed in your computer. Additionally, the game developers recommend somewhere around 1 GB of RAM in your system. The cheapest graphics card you can play it on is an AMD Radeon 9550. Futhermore, an NVIDIA GeForce GT 520 is recommended in order to run Ant Queen with the highest settings.
Ant Queen will run on PC system with XP SP2 and Higher (7, 8, 9, 10...) and upwards. Additionally it has Mac and Linux versions.