Up and Down system requirements state that you will need at least 1 GB of RAM. An Intel Pentium 4 2.00GHz CPU is required at a minimum to run Up and Down. You will need at least 200 MB of free disk space to install Up and Down. The cheapest graphics card you can play it on is an NVIDIA GeForce 6200.
Up and Down will run on PC system with Windows XP / Vista / 7 / 8 / 10 and upwards.